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Mutahari S M, Alemzada F. Current Practices and Future Perspectives in Intensity-Modulated Radiation Therapy: A Comprehensive Review. KJMS 2024; 9 (16) :9-22
URL: http://kjms.knu.edu.af/article-1-35-en.html

Intensity Modulated Radiotherapy (IMRT) is an advanced external beam radiotherapy technique that designed to accurately target tumors with a modulated radiation intensity. This approach modifies the radiation dose across the target area based on demanded dose, causing precisely delivering the necessary dose to the tumor while minimizing exposure to surrounding organs at risk. These benefits make it an essential utility to any advanced medical facility. Many studies have provided strong evidences indicating the clinical advantages of IMRT compared to other radiotherapy methods. At first, this treatment was seen as complicated and expensive. However, with new technologies for treatment and imaging, it has become clear that it can be quickly used in clinical settings. IMRT has evolved significantly; it is no longer a technique where non-uniform beam intensities were created solely with metal compensators. As of today, it incorporates advanced technologies such as multileaf collimators (MLCs), rotational fan beam delivery systems, and robotic arm linear accelerators to treat cancers. While IMRT has made significant advances, there are still some limitations, including its high costs, increased staff work, longer planning times, and the possibility of marginal miscalculations.