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Asghari S J, Hossaini Z, Jamil M, Noori M A, Askari S Z. Assessing the Prevalence of Hemophilia A Among Individuals at Kabul Central Blood Bank in 1402. KJMS 2024; 9 (17) :14-24
URL: http://kjms.knu.edu.af/article-1-38-en.html

Introduction: Hemophilia is a rare genetic disorder characterized by excessive bleeding and severe joint pain, primarily caused by deficiencies in coagulation factors VIII and IX. This disorder significantly impacts the quality of life for affected individuals, leading to recurrent bleeding episodes and long-term joint damage. This study aimed to investigate the prevalence of hemophilia A and its associated factors among individuals referred to the Kabul Central Blood Bank in 1402, providing valuable insights into the burden of this condition within the Afghan population.
Materials and Methods: This cross-sectional study was conducted in 1402, targeting individuals who presented at the Kabul Central Blood Bank. Demographic information, including age, gender, and medical history, was collected through structured interviews. Furthermore, coagulation factor levels were evaluated using standard laboratory diagnostic methods to confirm the diagnosis of hemophilia A. 
Results: The analysis of the collected data revealed that 201 individuals referred to the Central Blood Bank in 1402 were diagnosed with hemophilia A, indicating a significant prevalence of the disorder within this population.
Conclusion: The findings of this study highlight a concerning prevalence of hemophilia A in Afghanistan, underscoring the urgent need for improved screening, diagnosis, and treatment options for affected individuals. By emphasizing the necessity for enhanced diagnostic resources and targeted interventions, this research aims to better support those affected and improve overall health outcomes in the region. Additionally, the results provide a crucial foundation for future research and advocacy efforts aimed at addressing hemophilia and its challenges in Afghanistan.