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Sajjadi M. Investigating the methods of measuring the antioxidant capacity of medicinal plants. KJMS 2025; 9 (18) :22-31
URL: http://kjms.knu.edu.af/article-1-43-en.html

Antioxidants are important in protecting cells against damage caused by free radicals and reactive oxygen species. These molecules are directly linked to the development of chronic diseases, such as cancer, cardiovascular diseases, diabetes, and neurodegenerative disorders. Medicinal plants are valuable sources for the prevention and treatment of these diseases because of their rich antioxidant properties. This article reviews methods for measuring the antioxidant capacity of medicinal plants. Common methods for measuring antioxidant capacity include DPPH, ORAC, ABTS, and FRAP, which are used due to their simplicity and high speed for measuring antioxidant capacity compared with more complex methods. These tests are important to investigate compounds that can prevent cellular damage by reducing oxidative stress, which causes many chronic diseases. Measuring antioxidant capacity is an important tool for evaluating the potential for medicinal use in plants. The methods discussed in this article are about examining methods for measuring antioxidant effects and examining the advantages and disadvantages of each, and future research should continuously investigate their mechanisms of action and confirm their clinical effects in valid clinical trials.