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Amiri S H. Therapeutic Effects of Exercise on Blood Sugar Control in Type 2 Diabetes: A Systematic Review. KJMS 2025; 10 (20) :3-13
URL: http://kjms.knu.edu.af/article-1-86-en.html

This systematic review and meta-analysis aimed to evaluate the therapeutic effects of exercise on glycemic control in individuals with type 2 diabetes mellitus (T2DM). A comprehensive search of electronic databases identified studies that included randomized controlled trials (RCTs) focusing on various exercise interventions lasting more than eight weeks. A total of 52 studies involving 6,842 participants were included in the analysis. The findings demonstrated that regular physical activity significantly reduced glycated hemoglobin (HbA1c) levels, fasting blood sugar (FBS), and insulin resistance markers. Specifically, combined aerobic and resistance training interventions yielded the most substantial improvements in glycemic control, with reductions in HbA1c ranging from 0.5% to 0.9%. Additionally, exercise was associated with improvements in body mass index (BMI) and waist circumference, contributing to overall metabolic health. The results underscore the importance of incorporating structured exercise regimens into diabetes management protocols, highlighting exercise as a vital non-pharmacological intervention for optimizing glycemic control and enhancing the quality of life in T2DM patients. Future research should focus on long-term effects and the integration of exercise with dietary and behavioral modifications to further improve diabetes management strategies.